An Overview Of Literature On Corona Virus

This article presents an overview of information derived from various sources on the characteristics of Corona virus, its modes of transmission, clinical manifestations and ways for prevention as well as cure among human beings.  The literature has been scientifically compiled in a logical sequence so as to alleviate panic among people and help them fight this pandemic.

Morphology

Coronaviruses are large pleomorphic spherical particles with bulbous surface projections.

The diameter of the virus particles is around 120 nm.The envelope of the virus in electron micrographs appears as a distinct pair of electron dense shells.The viral envelope consists of a lipid bilayer where the membrane (M), envelope (E) and spike (S) structural proteins are anchored. A subset of coronaviruses (specifically the members of betacoronavirus subgroup A) also have a shorter spike-like surface protein called hemagglutinin esterase (HE). Inside the envelope, there is the nucleocapsid, which is formed from multiple copies of the nucleocapsid (N) protein, which are bound to the positive-sense single-stranded RNA genome in a continuous beads-on-a-string type conformation. The lipid bilayer envelope, membrane proteins, and nucleocapsid protect the virus when it is outside the host cell.

Full article in Ayurved Sutra Vol. 07 Issue 05

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